Tick-borne disease

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Tick-borne disease
Classification and external resources
Specialty Infectious disease
eMedicine emerg/584
Patient UK Tick-borne disease
MeSH D017282
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Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. Tick-borne illnesses are caused by infection with a variety of pathogens, including rickettsia and other types of bacteria, viruses, and protozoa. Because individual ticks can harbor more than one disease-causing agent, patients can be infected with more than one pathogen at the same time, compounding the difficulty in diagnosis and treatment. Currently (2015), there are 16 known tick-borne diseases of humans (four discovered since 2013).

As the incidence of tick-borne illnesses increases and the geographic areas in which they are found expand, it becomes increasingly important that health workers be able to distinguish the diverse, and often overlapping, clinical presentations of these diseases.

Diagnosis and treatment

In general, specific laboratory tests are not available to rapidly diagnose tick-borne diseases. Due to their seriousness, antibiotic treatment is often justified based on clinical presentation alone.

Exposure

Ticks tend to be more active during warmer months, though this varies by geographic region and climate. Areas with woods, bushes, high grass, or leaf litter are likely to have more ticks. Those bitten commonly experience symptoms such as body aches, fever, fatigue, joint pain, or rashes. People can limit their exposure to tick bites by wearing light-colored clothing (including pants and long sleeves), using insect repellent with 20%–30% DEET, tucking their pant legs into their socks, checking for ticks frequently, and washing and drying their clothing (in a hot dryer).[1] Another natural form of control for ticks is the guineafowl, a bird species which consumes mass quantities of ticks. So good animal husbandry can reduce tick prevalence in a high tick prevalence area.[citation needed]

Assessing Risk

For a person or companion animal to acquire a tick-borne disease requires that that individual gets bitten by a tick and that that tick feeds for a sufficient period of time. The feeding time required to transmit pathogens differs for different ticks and different pathogens. Transmission of the bacteria that causes Lyme disease is well understood to require a substantial feeding period.[2]

For an individual to acquire infection, the feeding tick must also be infected. Not all ticks are infected. In most places in the US, 30-50% of deer ticks will be infected with Borrelia burgdorferi (the agent of Lyme disease). Other pathogens are much more rare. Ticks can be tested for infection using a highly specific and sensitive qPCR procedure. Several commercial labs provide this service to individuals for a fee. The Laboratory of Medical Zoology (LMZ) is a non-profit lab at the University of Massachusetts that provides a comprehensive TickReport [3] for a variety of human pathogens and makes the data available to the public.[4] Those wishing to know the incidence of tick-borne disease in their town or state can search the LMZ surveillance database.[4]

Examples

Major tick-borne diseases include:

Bacteria

  • Lyme disease or Borreliosis
  • Relapsing fever (Tick-borne relapsing fever, different from Lyme disease due to different Borrelia species and ticks)
    • Organisms: Borrelia species Such as Borrelia hermsii, Borrelia parkeri, Borrelia duttoni, Borrelia miyamotoi
    • Vector: Ornithodoros species
    • Regions : Primarily in Africa, Spain, Saudi Arabia, Asia in and certain areas of Canada and the western United States
    • Symptoms: Relapsing fever typically presents as recurring high fevers, flu like symptoms, headaches, and muscular pain, with less common symptoms including rigors, joint pain, altered mentation, cough, sore throat, painful urination, and rash.[7]
    • Treatment: antibiotics are the treatment for relapsing fever, with doxycycline, tetracycline, or erythromycin being the treatment of choice.[8]
  • Typhus Several diseases caused by Rickettsia bacteria (below).
  • Rocky Mountain Spotted Fever
  • Helvetica Spotted fever
    • Organism: Rickettsia helvetica
    • Region(R Helvetica): Confirmed common in ticks in Sweden, Switzerland, France and in Laos[9]
    • Vector/Region(s)#1 : Ixodes ricinus is the main European vector[9]
    • Vector/Region(s)#2: Please add if more vectors are found.
    • Symptoms:Most often small red spots, other symptoms are fever, muscle pain, headache and respiratory problems[9]
    • Treatment: Broad band Antibiotic therapy are needed, it is likely that phenoxymethylpenicillin is sufficient.[9]
  • Ehrlichiosis anaplasmosis (formerly human granulocytic ehrlichiosis or HGE)
  • Tularemia
    • Organism: Francisella tularensis, A. americanum
    • Vector: D. andersoni, D. variabilis
    • Region (US): Southeast, South-Central, West, Widespread

Viruses

Protozoa

  • Babesiosis
    • Organism: Babesia microti, B. equi
    • Vector: I. scapularis, I. pacificus
    • Region (US): Northeast West Coast
  • Cytauxzoonosis
    • Organism: C. felis
    • Vector: D. variabilis (American Dog Tick)
    • Region (US): South, Southeast

Toxin

  • Tick paralysis
    • Cause: Toxin
    • Vector (US): D. andersoni, D. variabilis West
    • Region (US): East
    • Vector (Australia): Ixodes holocyclus[11]
    • Region (Australia): East

See also

References

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  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ 4.0 4.1 Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  7. ↑ Relapsing fever at eMedicine.
  8. ↑ Relapsing fever~treatment at eMedicine.
  9. ↑ 9.0 9.1 9.2 9.3 Lua error in package.lua at line 80: module 'strict' not found.
  10. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  11. ↑ Lua error in package.lua at line 80: module 'strict' not found.

External links

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