Transfusion hemosiderosis
| Transfusion hemosiderosis | |
|---|---|
| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| ICD-10 | T80.8 |
| ICD-9-CM | 999.8 |
| Patient UK | Transfusion hemosiderosis |
Transfusional hemosiderosis is the accumulation of iron in the liver and/or heart but also endocrine organs, in patients who receive or did receive frequent blood transfusions (such as those with thalassemia, sickle cell disease, leukemia, aplastic anemia or myelodysplastic syndrome).
Treatment
Treatment is by phlebotomy, erythrocytapheresis or chelation therapy with iron chelating agents such as deferoxamine, deferiprone or deferasirox.[1] If iron overload has caused end-organ damage, this is generally irreversible and may require transplantation.
Notable patients
Ted DeVita died of transfusional iron overload from too many blood transfusions.
See also
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
2. Lu JP, Hayashi K. Selective iron deposition in pancreatic islet B cells of transfusional iron-overloaded autopsy cases. Pathol Int. 1994 Mar;44(3):194-9.PubMed PMID 8025661.
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