Tritoqualine

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Tritoqualine
File:Tritoqualine.png
Systematic (IUPAC) name
7-amino-4,5,6-triethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 14504-73-5
ATC code R06AX21 (WHO)
PubChem CID: 72145
ChemSpider 65119
UNII F4MW5166YH YesY
Chemical data
Formula C26H32N2O8
Molecular mass 500.54 g/mol
  • CCOC1=C(C(=C(C2=C1C(OC2=O)C3C4=C(C5=C(C=C4CCN3C)OCO5)OC)N)OCC)OCC

Tritoqualine, also known as hypostamine, is an inhibitor of the enzyme histidine decarboxylase and therefore an atypical antihistamine, used for the treatment of urticaria and allergic rhinitis[1] with no known adverse effects.[citation needed]

References

  1. Randomized, placebo controlled study of tritoqualine (hypostamine*) in the treatment of perennial allergic rhinitis. A. Pradalier, V. Hentschel, S. Prouzeau, D. Legallais, G. Lefrançois. Revue Française d’Allergologie et d’Immunologie Clinique 43:175-179 (2003)


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