UR-AK49

UR-AK49

Systematic (IUPAC) name
3-cyclohexyl-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]propanamide
Identifiers
PubChem	CID: 25149433
ChemSpider	21486130 Y
ChEMBL	CHEMBL486974 Y
Synonyms	UR-AK49
Chemical data
Formula	C16H27N5O
Molecular mass	305.417 g/mol
SMILES c1c(nc[nH]1)CCCNC(=N)NC(=O)CCC2CCCCC2
InChI InChI=1S/C16H27N5O/c17-16(19-10-4-7-14-11-18-12-20-14)21-15(22)9-8-13-5-2-1-3-6-13/h11-13H,1-10H2,(H,18,20)(H3,17,19,21,22) Y Key:QBGKYFYOFBXHFM-UHFFFAOYSA-N Y
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UR-AK49 is a drug used in scientific research which acts as a potent antagonist for the Neuropeptide Y / Pancreatic polypeptide receptor Y₄, and also as a partial agonist at the histamine receptors H₁ and H₂. UR-AK49 is a pure antagonist at Y₄ with no partial agonist effects, and although it is only slightly selective for Y₄ over the related Y₁ and Y₅ receptors, as the first non-peptide Y₄ antagonist developed UR-AK49 is expected to be useful in the study of this receptor and its role in the body.

References

1. REDIRECT Template:Peptide receptor modulators