United Kingdom Model for End-Stage Liver Disease

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The United Kingdom Model for End-Stage Liver Disease or UKELD is a medical scoring system used to predict the prognosis of patients with chronic liver disease. It is used in the United Kingdom to help determine the need for liver transplantation.[1] It was developed from the MELD score, incorporating the serum sodium level.[2]

Determination

The UKELD score is calculated from the patient's INR, serum creatinine, serum bilirubin and serum sodium, according to the formula:[3]

(5.395 \times \ln INR) + (1.485 \times \ln creatinine) + (3.13 \times \ln bilirubin) - (81.565 \times \ln Na) + 435

Interpretation

Higher UKELD scores equate to higher one-year mortality risk. A UKELD score of 49 indicates a 9% one-year risk of mortality, and is the minimum score required to be added to the liver transplant waiting list in the U.K.[1] A UKELD score of 60 indicates a 50% chance of one-year survival.[2]

History

The UKELD score was developed in 2008 to aid in the selection of patients for liver transplantation in the U.K.[4]

See also

References

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  2. ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.

External links

  • Lua error in package.lua at line 80: module 'strict' not found. (Microsoft Excel file)
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