Aceperone

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Aceperone.svg
Systematic (IUPAC) name
N-({1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-phenyl-4-piperidinyl}methyl)acetamide
Identifiers
CAS Number 807-31-8
ATC code none
PubChem CID: 13122
ChemSpider 12570
UNII S69KXZ59AB
ChEMBL CHEMBL136298
Synonyms Acetabuton; R 3248
Chemical data
Formula C24H29FN2O2
Molecular mass 396.498 g/mol
  • Fc1ccc(cc1)C(=O)CCCN3CCC(c2ccccc2)(CC3)CNC(=O)C
  • InChI=1S/C24H29FN2O2/c1-19(28)26-18-24(21-6-3-2-4-7-21)13-16-27(17-14-24)15-5-8-23(29)20-9-11-22(25)12-10-20/h2-4,6-7,9-12H,5,8,13-18H2,1H3,(H,26,28)
  • Key:VDGZERMDPAAZEJ-UHFFFAOYSA-N
Physical data
Melting point 97 to 100 °C (207 to 212 °F) [1]

Aceperone is a neuroleptic drug of the butyrophenone class. It is an α-noradrenergic blocking drug developed by Janssen Pharmaceutica in the 1960s.[1]

Because of its learning impairment effects in animals, aceperone has been used as a tool in the study of the biochemical basis of learning.[2][3][4]

References

  1. ↑ 1.0 1.1 Alkoxylamino and alkoxycarbonylamino derivatives of 1(aroylalkyl)-4-arylpiperidines. Janssen, Paul A. J. (1961) BE 606849 
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.

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