Altrenogest
From Infogalactic: the planetary knowledge core
200px | |
Names | |
---|---|
IUPAC name
(8S,13S,14S,17R)-17-hydroxy-13-methyl-17-prop-2-enyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
|
|
Other names
Allyltrenbolone; Regumate; RU 2267
|
|
Identifiers | |
850-52-2 | |
ChEMBL | ChEMBL1315492 |
ChemSpider | 8216634 |
Jmol 3D model | Interactive image Interactive image |
KEGG | D02840 |
PubChem | 10041070 |
UNII | 2U0X0JA2NB |
|
|
|
|
Properties | |
C21H26O2 | |
Molar mass | 310.42994 |
Pharmacology | |
ATCvet code | QG03 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
|
verify (what is ?) | |
Infobox references | |
Altrenogest (INN, USAN, BAN) (brand name Regumate), also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals.[1][2][3]
Syntheses
This compound can be prepared by two different ways:
- The Grignard reaction of 3-oximino-17-oxoestre-4,9,11-triene (I) with allylmagnesium bromide in ether - benzene gives 3-oximino-17alpha-allyl-17-hydroxyestra-4,9,11-triene (2), which pyruvic acid - acetic acid .
- The dehydration of 17alpha-allyl-11beta,17beta-dihydroxyestra-4,9-dien-3-one (IV) eith refluxing aqueous 60% formic acid.
See also
References
<templatestyles src="Asbox/styles.css"></templatestyles>