B3GNT1

Beta-1,4-glucuronyltransferase 1
Identifiers
Symbols	B4GAT1 ; B3GN-T1; B3GNT1; B3GNT6; BETA3GNTI; MDDGA13; iGAT; iGNT
External IDs	OMIM: 605517 MGI: 1919680 HomoloGene: 38239 GeneCards: B4GAT1 Gene
EC number	2.4.1.149
Gene ontology Molecular function • N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity • glucuronosyltransferase activity • metal ion binding Cellular component • Golgi membrane • Golgi apparatus • integral component of Golgi membrane • extracellular exosome Biological process • carbohydrate metabolic process • axon guidance • keratan sulfate biosynthetic process • glycosaminoglycan metabolic process • poly-N-acetyllactosamine biosynthetic process • protein O-linked mannosylation • keratan sulfate metabolic process • small molecule metabolic process Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE B3GNT1 203188 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11041	108902
Ensembl	ENSG00000174684	ENSMUSG00000047379
UniProt	O43505	Q8BWP8
RefSeq (mRNA)	NM_006876	NM_175383
RefSeq (protein)	NP_006867	NP_780592
Location (UCSC)	Chr 11: 66.35 – 66.35 Mb	Chr 19: 5.04 – 5.04 Mb
PubMed search	[1]	[2]

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the B3GNT1 gene.

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen.