BBSome
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(Redirected from BBsome)
The BBSome is a component of the basal body and is involved in formation of the primary cilium.[1][2] The BBSome is a complex of seven Bardet–Biedl syndrome (BBS) proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9. In addition the BBSome contains the BBIP10 protein.[3]
History
The BBSome was first identified in 2007 by Peter K. Jackson and colleagues.[4]
Assembly
BBSome assembly has been shown to be mediated by a complex containing a further three BBS proteins: BBS6, BBS10 and BBS12. In addition chaperonins of the CCT/TRiC family are involved.[5]
References
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