Cinnamtannin B1

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Cinfgfannin B1
Chemical structure of cinnamtannin B1
Identifiers
ChemSpider 417255 N
Jmol 3D model Interactive image
PubChem 475277
  • InChI=1S/C45H36O18/c46-18-10-27(54)33-31(11-18)62-45(17-3-6-22(49)26(53)9-17)44(59)38(33)36-32(63-45)14-29(56)35-37(39(58)41(61-43(35)36)16-2-5-21(48)25(52)8-16)34-28(55)13-23(50)19-12-30(57)40(60-42(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,30,37-41,44,46-59H,12H2/t30-,37+,38-,39-,40-,41-,44-,45+/m1/s1 N
    Key: BYSRPHRKESMCPO-LQNPQWRQSA-N N
  • InChI=1/C45H36O18/c46-18-10-27(54)33-31(11-18)62-45(17-3-6-22(49)26(53)9-17)44(59)38(33)36-32(63-45)14-29(56)35-37(39(58)41(61-43(35)36)16-2-5-21(48)25(52)8-16)34-28(55)13-23(50)19-12-30(57)40(60-42(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,30,37-41,44,46-59H,12H2/t30-,37+,38-,39-,40-,41-,44-,45+/m1/s1
    Key: BYSRPHRKESMCPO-LQNPQWRQBE
  • Oc%10cc(O)c1C4c2c(OC(C4O)Oc1c%10)c(cc7O)ccc7O)cc(O)c(c2OC(C3O)c(cc8O)ccc8O)C3c(c(O)cc5O)c(c5CC6O)OC6c(cc9O)ccc9O
Properties
C45H36O18
Molar mass 864.75 g/mol
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Cinnamtannin B1 is a condensed tannin found in Cinnamomum verum. It is a type A proanthocyanidin.[1]

Cinnamon could have some pharmacological effects in the treatment of type 2 diabetes mellitus and insulin resistance. The plant material used in the study was mostly from Chinese cinnamon (see Chinese cinnamon's medicinal uses).[2][3] Recent studies in phytochemistry have indicated that cinnamtannin B1 isolated from C. Verum bears possible therapeutic effect on type 2 diabetes,[4] with the exception of the postmenopausal patients studied on Cinnamomum aromaticum.[5]

Cinnamtannin B1 possesses several phenolic hydroxyl groups and is reported to exhibit antioxidant property, antimicrobial activities, and anti-platelet aggregation[6] that may protect damaged tissues in wounds[7]

References

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  6. López, J. J., Jardín, I., Salido, G. M., & Rosado, J. A. (2008). Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor. Life sciences, 82(19), 977-982. doi:10.1016/j.lfs.2008.03.009
  7. Fujita K, Kuge K, Ozawa N, Sahara S, Zaiki K, Nakaoji K, et al. (2015) Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice. PLoS ONE 10(12): e0144166. doi:10.1371/journal.pone.0144166


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