Enzyme activator

Bacillus stearothermophilus phosphofructokinase. PDB: 6PFK​.

Enzyme activators are molecules that bind to enzymes and increase their activity. They are the opposite of enzyme inhibitors. These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism. An example of an enzyme activator working in this way is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and increases the rate of glycolysis in response to the hormone insulin.

See also

• Enzyme inducer
• Effector (biology)