Ethyl diazoacetate

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Ethyl diazoacetate[1][2]
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Names
IUPAC name
Ethyl diazoacetate
Other names
2-diazoacetic acid ethyl ester
Identifiers
623-73-4 YesY
ChemSpider 11692 YesY
Jmol 3D model Interactive image
  • InChI=1S/C4H6N2O2/c1-2-8-4(7)3-6-5/h3H,2H2,1H3 YesY
    Key: YVPJCJLMRRTDMQ-UHFFFAOYSA-N YesY
  • InChI=1/C4H6N2O2/c1-2-8-4(7)3-6-5/h3H,2H2,1H3
    Key: YVPJCJLMRRTDMQ-UHFFFAOYAC
  • CCOC(=O)C=[N+]=[N-]
Properties
C4H6N2O2
Molar mass 114.10 g/mol
Appearance yellow oil
Density 1.085 g/cm3
Melting point −22 °C (−8 °F; 251 K)
Boiling point 140 to 141 °C (284 to 286 °F; 413 to 414 K) 720 mmHg
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Ethyl diazoacetate (N=N=CHC(O)OC2H5) is a diazo compound and a reagent in organic chemistry. It was discovered by Theodor Curtius in 1883.[3] The compound can be prepared by reaction of the ethyl ester of glycine with sodium nitrite and sodium acetate in water.

Ethyl diazoacetate synthesis

It is used in the cyclopropanation of alkenes.

Although the compound is hazardous it is used in chemical industry.[4] Procedures for safe industrial handling have been published [5]

Applications

Tranylcypromine, Trovafloxacin

References

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