Fluticasone
From Infogalactic: the planetary knowledge core
<templatestyles src="Module:Hatnote/styles.css"></templatestyles>
![]() |
|
![]() |
|
Systematic (IUPAC) name | |
---|---|
S-Fluoromethyl (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioate
|
|
Clinical data | |
AHFS/Drugs.com | monograph |
Pregnancy category |
|
Legal status | |
Routes of administration |
Intranasal, inhaled, topical cream or ointment |
Pharmacokinetic data | |
Bioavailability | 0.51% (Intranasal) |
Protein binding | 91% |
Metabolism | Intranasal Hepatic (CYP3A4-mediated) |
Biological half-life | 10 hours |
Excretion | Renal |
Identifiers | |
CAS Number | 90566-53-3 ![]() Template:CAS (propionate) |
ATC code | D07AC17 (WHO) R01AD08 R03BA05 |
PubChem | CID: 5311101 |
IUPHAR/BPS | 6699 |
DrugBank | DB00588 ![]() |
ChemSpider | 4470631 ![]() |
UNII | CUT2W21N7U ![]() |
KEGG | D07981 ![]() |
ChEBI | CHEBI:5134 ![]() |
ChEMBL | CHEMBL1201396 ![]() |
Chemical data | |
Formula | C22H27F3O4S |
Molecular mass | 444.508 g/mol |
|
|
|
|
![]() ![]() |
Fluticasone is a synthetic glucocorticoid.[1] Both the furoate and propanoate ester prodrugs, fluticasone furoate and fluticasone propanoate, are used as topical anti-inflammatories:[2]