H1299
From Infogalactic: the planetary knowledge core
H1299, also known as NCI-H1299[1][2] or CRL-5803,[3] is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research.[4]
As with other immortalized cell lines, H1299 cells can divide indefinitely. These cells have a homozygous partial deletion of the TP53 gene and as a result, do not express the tumor suppressor p53 protein which in part accounts for their proliferative propensity.[5] These cells have also been reported to secrete the peptide hormone neuromedin B (NMB), but not gastrin releasing peptide (GRP).[4]
References
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External links
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