Hematoxylin body
From Infogalactic: the planetary knowledge core
In diagnostic pathology, a hematoxylin body, or LE body, is a dense, homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded nuclear material from an injured cell, along with autoantibodies and a limited amount of cytoplasm.[1][2][3]
Hematoxylin bodies occur in systemic lupus erythematosus. The hematoxylin body may be green, blue, or purple with the Papanicolaou stain and magenta with Romanowsky stains.[4] The material has a positive Feulgen stain reaction, which is typical of DNA.[5] The material may be extracellular or may be ingested by leukocytes, which are then known as LE cells.[2][6][7]
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ 2.0 2.1 Hematoxylin body. Medical Dictionary. [1]
- ↑ Moreland, LW. Rheumatology and Immunology Therapy Springer Berlin Heidelberg 2004 page 384 ISBN 9783540206255 http://dx.doi.org/10.1007/3-540-29662-X_1191
- ↑ Cibas ES, Ducatman BS. Cytology: Diagnostic Principles and Clinical Correlates. Elsevier Health Sciences. 2013. Pages 132-133 ISBN 9781455750795 [2]
- ↑ Hollander JL. Arthritis and allied conditions: a textbook of rheumatology. 1966 Page 100 and 784 [3]
- ↑ Wallace DJ, Hahn B. (editors). Dubois' Lupus Erythematosus. Lippincott Williams & Wilkins, 2007. ISBN 9780781793940
- ↑ Robbins & Cotran Pathologic Basis of Disease. Vinay Kumar V, Abbas AK, Aster JC. Elsevier Health Sciences, 2014. Edition 9, revised. pages 222 and 225. ISBN 9780323296359
External links
- American College of Rheumatology: Systemic Lupus Erythematosus: Myocardium, Hematoxylin Body
- Systemic lupus erythematosus: hematoxylin body; peripheral glomerular loop: hhomogenous eosinophilic intracytoplasmic inclusions
