Ian Calman Muir MacLennan
| Ian Calman Muir MacLennan | |
|---|---|
| Born | December 30, 1939 |
| Fields | Immunology |
| Institutions | University of Birmingham |
| Known for | contributions to immunology discovered marginal zone B-cells |
| Notable awards | FRS (2012) |
Ian Calman Muir MacLennan is Emeritus Professor of Immunology at the University of Birmingham MRC Centre for Immune Regulation in Birmingham, UK.
He was born on December 30, 1939.[1] He has made pioneering contributions to immunology and was the first to discover marginal zone B-cells.
He was made a Commander of the Order of the British Empire in the Queen's Birthday Honours in 2005.[2] He was elected a Fellow of the Royal Society (FRS) in 2012, his nomination reads:<templatestyles src="Template:Blockquote/styles.css" />
Ian MacLennan has made several landmark contributions to immunology and especially our understanding of antibody production. His classic experiments led him propose a role for germinal centres in affinity maturation of antibody responses by a process of hypermutation followed by antigen-mediated selection. Subsequently, he identified the basis of the multi-step selection process that protects against autoantibody production. He also first discovered marginal zone B cells and identified how they counter encapsulated bacterial infection. His early work revealed and characterized the cells now termed NK cells and their capacity to kill antibody-coated nucleated cells.
References
<templatestyles src="Asbox/styles.css"></templatestyles>
 |
This article about a British scientist is a stub. You can help Wikipedia by expanding it. |
