Lurosetron

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Lurosetron
File:Lurosetron.png
Systematic (IUPAC) name
6-fluoro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
Identifiers
CAS Number 128486-54-4 N
Template:CAS (mesylate)
ATC code none
PubChem CID: 172999
ChemSpider 151068 N
UNII G694G740ZP YesY
KEGG D04821 YesY
Chemical data
Formula C17H17FN4O
Molecular mass 312.341 g/mol
  • CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=C(N3C)C(=CC=C4)F
  • InChI=1S/C17H17FN4O/c1-10-13(20-9-19-10)8-22-7-6-14-15(17(22)23)11-4-3-5-12(18)16(11)21(14)2/h3-5,9H,6-8H2,1-2H3,(H,19,20) N
  • Key:NUMKWGDDRWJQMY-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Lurosetron (INN) is a serotonin 5-HT3 receptor antagonist.[1]

Synthesis

File:Lurosetron synthesis.svg
Lurosetron synthesis: EP 0353983 

References

  1. Prakash SP, Cable KM, Correa ID, Fellows L, Montgomery S, Newman JJ, Waterhouse L, Wells GN, Sutherland DR. Synthesis of isotopically labelled pyridoindolone 5-HT3 receptor antagonists. Journal of Labelled Compounds and Radiopharmaceuticals. 1995; 36(10):993-1007.


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