Luzindole

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Luzindole
File:Luzindole.svg
Systematic (IUPAC) name
N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
Clinical data
Legal status
  • Non-regulated
Identifiers
CAS Number 117946-91-5
ATC code None
PubChem CID: 122162
ChemSpider 108959
ChEBI CHEBI:131788 YesY
Chemical data
Formula C19H20N2O
Molecular mass 292.375 g/mol
  • O=C(NCCc2c1ccccc1nc2Cc3ccccc3)C
  • InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
  • Key:WVVXBPKOIZGVNS-UHFFFAOYSA-N

Luzindole (N-0774), (N-acetyl-2-benzyltryptamine), is a drug used in scientific research to study the role of melatonin in the body. Luzindole acts as a selective melatonin receptor antagonist,[1] with approximately 11- to 25-fold greater affinity for the MT2 over the MT1 receptor.[2][3] In animal studies, it has been observed to disrupt the circadian rhythm as well as produce antidepressant effects.[2][4]

References

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  2. ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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