Meesmann corneal dystrophy
From Infogalactic: the planetary knowledge core
| Meesmann juvenile epithelial corneal dystrophy | |
|---|---|
Multiple opaque spots in the corneal epithelium
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| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| ICD-9-CM | 371.51 |
| OMIM | 122100 |
| DiseasesDB | 31962 |
| Patient UK | Meesmann corneal dystrophy |
| MeSH | D053559 |
Meesmann corneal dystrophy, also Stocker-Holt dystrophy, is a type of corneal dystrophy and a keratin disease.
It is named for German ophthalmologist Alois Meesmann (1888-1969).[1][2]
It is sometimes called "Meesmann-Wilke syndrome", after the joint contribution of Meesmann and Wilke.[1][3]
Genetics
It has been associated with genes KRT3 and KRT12 located on chromosome 12 and 17 respectively.[4]
Clinical presentation
This slowly progressive disorder is characterized by small cysts in the epithelium of the cornea. Patients with Meesmann corneal dystrophy are intolerant of contact lenses, as these devices directly traumatize the corneal epithelium.
See also
References
- ↑ 1.0 1.1 synd/3139 at Who Named It?
- ↑ A. Meesmann. Klinische und anatomische Untersuchungen über eine bisher unbekannte, dominant vererbte Dystrophia epithelialis corneae. Bericht der Deutschen ophthalmologischen Gesellschaft, Heidelberg, 1938, 52: 154-158.
- ↑ A. Meesmann, F. Wilke. Klinische und anatomische Untersuchungen über eine bisher unbekannte, dominant vererbte Epithel Dystrophie der Horn haut. Klinische Monatsblätter für Augenheilkunde, Stuttgart, 1939, 103: 361-391.
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 122100
