Nucleoporin 35

Nucleoporin 35kDa
250px PDB rendering based on 1wwh.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 4LIR
Identifiers
Symbols	NUP35 ; MP-44; MP44; NP44; NUP53
External IDs	OMIM: 608140 MGI: 1916732 HomoloGene: 44517 GeneCards: NUP35 Gene
Gene ontology Molecular function • protein binding Cellular component • nuclear envelope • nuclear pore • nuclear lamina • nucleoplasm • plasma membrane • nuclear membrane • intracellular membrane-bounded organelle • intermediate filament cytoskeleton Biological process • mitotic cell cycle • carbohydrate metabolic process • mitotic nuclear envelope disassembly • hexose transport • gene expression • regulation of glucose transport • protein transport • glucose transport • viral process • protein sumoylation • viral life cycle • viral transcription • cytokine-mediated signaling pathway • cellular response to heat • post-translational protein modification • cellular protein metabolic process • small molecule metabolic process • mRNA transport • transmembrane transport • regulation of cellular response to heat Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	129401	69482
Ensembl	ENSG00000163002	ENSMUSG00000026999
UniProt	Q8NFH5	Q8R4R6
RefSeq (mRNA)	NM_001008544	NM_001190179
RefSeq (protein)	NP_001274513	NP_001177108
Location (UCSC)	Chr 2: 183.12 – 183.16 Mb	Chr 2: 80.62 – 80.66 Mb
PubMed search	[1]	[2]

Nucleoporin 35 (Nup35) is a protein that in humans is encoded by the NUP35 gene.

Background

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.