Oxyclozanide

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Oxyclozanide
Oxyclozanide.png
Names
IUPAC name
2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
Identifiers
2277-92-1 YesY
ChemSpider 15904 N
Jmol 3D model Interactive image
KEGG D08320 YesY
PubChem 16779
UNII 1QS9G4876X YesY
  • InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22) N
    Key: JYWIYHUXVMAGLG-UHFFFAOYSA-N N
  • InChI=1/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
    Key: JYWIYHUXVMAGLG-UHFFFAOYAW
  • C1=C(C=C(C(=C1Cl)O)NC(=O)C2=C(C(=CC(=C2Cl)Cl)Cl)O)Cl
Properties
C13H6Cl5NO3
Molar mass 401.45 g·mol−1
Pharmacology
ATCvet code QP52AG06
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Oxyclozanide is a salicylanilide anthelmintic. It is used in the treatment and control of fascioliasis in ruminants mainly domestic animals such as cattle, sheep, and goats. It mainly acts by uncoupling of oxidative phosphorylation in flukes.[1] Along with niclosamide, another tapeworm drug, it has been recently found to display "strong in vivo and in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA)".[2]

References

  1. CID 16779 from PubChem
  2. Lua error in package.lua at line 80: module 'strict' not found.


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