Phosphoribosylaminoimidazole synthetase

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Phosphoribosylaminoimidazole synthetase
Identifiers
EC number 2.1.2.2
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In the field of enzymology, phosphoribosylaminoimidazole synthetase is an enzyme that catalyzes the chemical reaction:

10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide \rightleftharpoons tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide

This enzyme is required for the de novo biosynthesis of purines.

References

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