Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
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Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) | |||||||||
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Identifiers | |||||||||
EC number | 4.3.3.6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (EC 4.3.3.6, PdxST) is an enzyme with systematic name D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase.[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction
- D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine
pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate (overall reaction)
- (1a) L-glutamine + H2O
L-glutamate + NH3
- (1b) D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3
pyridoxal 5'-phosphate + 4 H2O + phosphate
The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate.
References
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External links
- Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) at the US National Library of Medicine Medical Subject Headings (MeSH)