Quisinostat

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File:Quisinostat.svg
Systematic (IUPAC) name
N-Hydroxy-2-[4-({[(1-methyl-1H-indol-3-yl)methyl]amino}methyl)-1-piperidinyl]-5-pyrimidinecarboxamide
Identifiers
ATC code None
PubChem CID: 11538455
ChemSpider 9713236
Synonyms JNJ-26481585
Chemical data
Formula C21H26N6O2
Molecular mass 394.470 g/mol
  • O=C(NO)c1cnc(nc1)N2CCC(CC2)CNCc4c3ccccc3n(c4)C
  • InChI=1S/C21H26N6O2/c1-26-14-17(18-4-2-3-5-19(18)26)11-22-10-15-6-8-27(9-7-15)21-23-12-16(13-24-21)20(28)25-29/h2-5,12-15,22,29H,6-11H2,1H3,(H,25,28)
  • Key:PAWIYAYFNXQGAP-UHFFFAOYSA-N

Quisinostat (USAN;[1] development code JNJ-26481585) is an experimental drug candidate for the treatment of cancer. It is a "second generation" histone deacetylase inhibitor with antineoplastic activity.[2][3][4]

References

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