RECK
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Reversion-inducing-cysteine-rich protein with kazal motifs, also known as RECK, is a human gene,[1] thought to be a metastasis suppressor.
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.[1] It is one of the targets of an oncomiR, MIRN21.
References
Further reading
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