SMC2

Structural maintenance of chromosomes 2
Identifiers
Symbols	SMC2 ; CAP-E; CAPE; SMC-2; SMC2L1
External IDs	OMIM: 605576 MGI: 106067 HomoloGene: 4705 GeneCards: SMC2 Gene
Gene ontology Molecular function • protein binding • ATP binding • protein heterodimerization activity Cellular component • nuclear chromosome • condensed chromosome • condensin complex • nucleus • nucleoplasm • cytoplasm • cytosol • extracellular exosome Biological process • mitotic cell cycle • mitotic chromosome condensation • meiotic chromosome condensation • meiotic chromosome segregation • cell division • kinetochore organization Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE SMC2 213253 at tn.png
File:PBB GE SMC2 204240 s at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10592	14211
Ensembl	ENSG00000136824	ENSMUSG00000028312
UniProt	O95347	Q8CG48
RefSeq (mRNA)	NM_001042550	NM_001301412
RefSeq (protein)	NP_001036015	NP_001288341
Location (UCSC)	Chr 9: 104.09 – 104.14 Mb	Chr 4: 52.44 – 52.49 Mb
PubMed search	[1]	[2]

Structural maintenance of chromosomes protein 2 (SMC-2) also known as chromosome-associated protein E (CAP-E) is a protein that in humans is encoded by the SMC2 gene.

SMC-2 is a subunit of condensin I and II, large protein complexes involved in chromosome condensation.

Interactions

SMC2 has been shown to interact with DNMT3B.