STARD10

StAR-related lipid transfer (START) domain containing 10
Identifiers
Symbols	STARD10 ; CGI-52; NY-CO-28; PCTP2; SDCCAG28
External IDs	MGI: 1860093 HomoloGene: 4841 GeneCards: STARD10 Gene
Gene ontology Molecular function • protein binding • lipid binding Cellular component • cytosol • microvillus • membrane • intercellular canaliculus Biological process • bile acid secretion • positive regulation of peroxisome proliferator activated receptor signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE STARD10 gnf1h00096 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10809	56018
Ensembl	ENSG00000214530	ENSMUSG00000030688
UniProt	Q9Y365	Q9JMD3
RefSeq (mRNA)	NM_006645	NM_019990
RefSeq (protein)	NP_006636	NP_064374
Location (UCSC)	Chr 11: 72.75 – 72.79 Mb	Chr 7: 101.32 – 101.35 Mb
PubMed search	[1]	[2]

StAR-related lipid transfer protein 10 (STARD10) or PCTP-like protein is a lipid transfer protein that in humans is encoded by the STARD10 gene. The protein derives its name from the fact that the molecule contains a START domain. As part of the StarD2 subfamily, StarD10 can transport the lipids phosphatidylcholine and phosphatidylethanolamine between membranes in solution. Casein kinase II phosphorylates the protein on its serine at position 184.

The function of StarD10 in the cell is not yet understood. Its expression is associated with cancer, but the nature of its role is unclear. Most recent data indicate that loss of StarD10 expression in breast cancer is associated with poor outcomes in patients.