STK24
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Serine/threonine-protein kinase 24 is an enzyme that in humans is encoded by the STK24 gene.[1][2][3]
The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000).[supplied by OMIM][3]
Interactions
STK24 has been shown to interact with PDCD10,[4][5][6] TRAF3IP3,[6] STRN3,[5][6] MOBKL3,[5][6] STRN,[5][6] SLMAP,[5][6] PPP2R1A,[5][6] CTTNBP2NL,[6] FAM40A[5][6] and STRN4.[5][6]
References
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Further reading
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