Sulfanegen

Sulfanegen

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Names
IUPAC name 2,5-Dihydroxy-1,4-dithiane-2,5-dicarboxylic acid
Identifiers
CAS Number	80003-64-1
ChemSpider	29395474
Jmol 3D model	Interactive image
PubChem	24830990
InChI InChI=1S/C6H8O6S2/c7-3(8)5(11)1-13-6(12,2-14-5)4(9)10/h11-12H,1-2H2,(H,7,8)(H,9,10) Key: GYZMXMSJOZUNEQ-UHFFFAOYSA-N InChI=1/C6H8O6S2/c7-3(8)5(11)1-13-6(12,2-14-5)4(9)10/h11-12H,1-2H2,(H,7,8)(H,9,10) Key: GYZMXMSJOZUNEQ-UHFFFAOYAO
SMILES C1C(SCC(S1)(C(=O)O)O)(C(=O)O)O
Properties
Chemical formula	C6H8O6S2
Molar mass	240.24 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Sulfanegen is an experimental antidote for cyanide poisoning. It is being studied as a prodrug for 3-mercaptopyruvic acid (3-MP). 3-MP has been studied as a potential treatment for cyanide poisoning, but the half-life is too short for it to be clinically effective. Instead, alternative chemicals such as sulfanegen, the hemithioacetal cyclic dimer of 3-MP, are being evaluated that produce 3-MP in vivo to compensate for the short half-life of 3-MP itself.

Sulfanegen has been shown to be effective in animal studies. It is being studied as the disodium salt, sulfanegen sodium, and the triethanolamine salt, sulfanegen TEA. One advantage various sulfanegen formulations have over existing treatments for acute cyanide poisoning is that they might be administered by intramuscular injection or orally rather than by intravenous infusion.