TDRD7

Tudor domain containing 7
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 3RCO
Identifiers
Symbols	TDRD7 ; CATC4; PCTAIRE2BP; TRAP
External IDs	OMIM: 611258 MGI: 2140279 HomoloGene: 8618 GeneCards: TDRD7 Gene
Gene ontology Molecular function • mRNA binding • protein binding • protein N-terminus binding Cellular component • cytoplasm • mitochondrial matrix • chromatoid body • ribonucleoprotein granule • P granule Biological process • lens morphogenesis in camera-type eye • germ cell development • spermatogenesis • posttranscriptional regulation of gene expression • lens fiber cell differentiation Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE TDRD7 213361 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23424	100121
Ensembl	ENSG00000196116	ENSMUSG00000035517
UniProt	Q8NHU6	Q8K1H1
RefSeq (mRNA)	NM_001302884	NM_001290475
RefSeq (protein)	NP_001289813	NP_001277404
Location (UCSC)	Chr 9: 97.41 – 97.5 Mb	Chr 4: 45.97 – 46.03 Mb
PubMed search	[1]	[2]

Tudor domain-containing protein 7 is a protein that in humans is encoded by the TDRD7 gene.

In melanocytic cells TDRD7 gene expression may be regulated by MITF.

Gene polymorphism

Various single nucleotide polymorphisms (SNPs) of the TDRD7 gene have been identified and for some of them an association with lower susceptibility to age-related cataract was shown.

Interactions

TDRD7 has been shown to interact with TACC1.