Template:PBB/27040
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<templatestyles src="Module:Infobox/styles.css"></templatestyles>
Linker for activation of T cells
Identifiers
Symbols
LAT
; LAT1; pp36
External IDs
OMIM
:
602354
MGI
:
1342293
HomoloGene
:
7811
ChEMBL
:
5779
GeneCards
:
LAT Gene
Gene ontology
Molecular function
•
SH3/SH2 adaptor activity
•
protein binding
•
protein kinase binding
Cellular component
•
immunological synapse
•
plasma membrane
•
cell-cell junction
•
COP9 signalosome
•
integral component of membrane
•
mast cell granule
•
membrane raft
Biological process
•
adaptive immune response
•
lymphocyte homeostasis
•
inflammatory response
•
immune response
•
integrin-mediated signaling pathway
•
Ras protein signal transduction
•
blood coagulation
•
positive regulation of signal transduction
•
gene expression
•
calcium-mediated signaling
•
platelet activation
•
intracellular signal transduction
•
Fc-epsilon receptor signaling pathway
•
T cell activation
•
mast cell degranulation
•
innate immune response
•
positive regulation of protein kinase activity
•
T cell receptor signaling pathway
•
regulation of T cell activation
Sources:
Amigo
/
QuickGO
Orthologs
Species
Human
Mouse
Entrez
27040
16797
Ensembl
ENSG00000213658
ENSMUSG00000030742
UniProt
O43561
O54957
RefSeq (mRNA)
NM_001014987
NM_010689
RefSeq (protein)
NP_001014987
NP_034819
Location (UCSC)
Chr 16:
28.98 – 28.99 Mb
Chr 7:
126.36 – 126.37 Mb
PubMed
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[1]
[2]
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Category
:
Human protein templates
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