Template:PBB/340273

ATP-binding cassette, sub-family B (MDR/TAP), member 5
Identifiers
Symbols	ABCB5 ; ABCB5alpha; ABCB5beta; EST422562
External IDs	OMIM: 611785 HomoloGene: 83488 IUPHAR: 772 ChEMBL: 1772928 GeneCards: ABCB5 Gene
EC number	3.6.3.44
Gene ontology Molecular function • ATP binding • efflux transmembrane transporter activity • ATPase activity, coupled to transmembrane movement of substances Cellular component • plasma membrane • integral component of plasma membrane Biological process • antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent • antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent • antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent • positive regulation of antigen processing and presentation of peptide antigen via MHC class I • metabolic process • cell differentiation • regulation of membrane potential • compound eye corneal lens development • transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	340273	77706
Ensembl	ENSG00000004846	ENSMUSG00000072791
UniProt	Q2M3G0	B5X0E4
RefSeq (mRNA)	NM_001163941	NM_029961
RefSeq (protein)	NP_001157413	NP_084237
Location (UCSC)	Chr 7: 20.62 – 20.78 Mb	Chr 12: 118.87 – 118.97 Mb
PubMed search	[1]	[2]