Template:PBB/344

Apolipoprotein C-II
PDB rendering based on 1by6.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1BY6, 1I5J, 1O8T, 1SOH
Identifiers
Symbols	APOC2 ; APO-CII; APOC-II
External IDs	OMIM: 608083 MGI: 88054 HomoloGene: 47928 GeneCards: APOC2 Gene
Gene ontology Molecular function • lipid binding • phospholipase activator activity • protein homodimerization activity • phospholipase binding • lipase inhibitor activity • lipoprotein lipase activator activity Cellular component • extracellular region • extracellular space • early endosome • very-low-density lipoprotein particle • low-density lipoprotein particle • intermediate-density lipoprotein particle • spherical high-density lipoprotein particle • chylomicron • extracellular exosome Biological process • retinoid metabolic process • phototransduction, visible light • positive regulation of phospholipase activity • positive regulation of triglyceride catabolic process • positive regulation of very-low-density lipoprotein particle remodeling • negative regulation of very-low-density lipoprotein particle clearance • lipid catabolic process • negative regulation of cholesterol transport • cholesterol efflux • phospholipid efflux • triglyceride-rich lipoprotein particle remodeling • chylomicron remodeling • very-low-density lipoprotein particle remodeling • chylomicron remnant clearance • high-density lipoprotein particle clearance • lipoprotein metabolic process • cholesterol homeostasis • negative regulation of catalytic activity • reverse cholesterol transport • small molecule metabolic process • positive regulation of fatty acid biosynthetic process • negative regulation of lipid metabolic process • negative regulation of receptor-mediated endocytosis • positive regulation of lipoprotein lipase activity • positive regulation of phospholipid catabolic process • triglyceride homeostasis Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	344	11813
Ensembl	ENSG00000224916	ENSMUSG00000002992
UniProt	P02655	Q05020
RefSeq (mRNA)	NM_000483	NM_001277944
RefSeq (protein)	NP_000474	NP_001264873
Location (UCSC)	Chr 19: 44.94 – 44.95 Mb	Chr 7: 19.67 – 19.68 Mb
PubMed search	[1]	[2]