Template:PBB/5187

Period circadian clock 1
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1UL6
Identifiers
Symbols	PER1 ; PER; RIGUI; hPER
External IDs	OMIM: 602260 MGI: 1098283 HomoloGene: 1966 GeneCards: PER1 Gene
Gene ontology Molecular function • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcription factor activity, transcription factor binding • transcription factor binding • kinase binding • chromatin DNA binding • ubiquitin protein ligase binding • E-box binding Cellular component • nucleus • cytoplasm Biological process • negative regulation of transcription from RNA polymerase II promoter • regulation of sodium ion transport • transcription, DNA-templated • circadian rhythm • entrainment of circadian clock • posttranscriptional regulation of gene expression • circadian regulation of gene expression • regulation of hair cycle • regulation of circadian rhythm • negative regulation of I-kappaB kinase/NF-kappaB signaling • entrainment of circadian clock by photoperiod • histone H3 acetylation • histone H4 acetylation • negative regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • negative regulation of JNK cascade • response to cAMP • histone H3 deacetylation • circadian regulation of translation • regulation of cytokine production involved in inflammatory response • regulation of p38MAPK cascade • negative regulation of glucocorticoid receptor signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE PER1 36829 at tn.png
File:PBB GE PER1 202861 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5187	18626
Ensembl	ENSG00000179094	ENSMUSG00000020893
UniProt	O15534	O35973
RefSeq (mRNA)	NM_002616	NM_001159367
RefSeq (protein)	NP_002607	NP_001152839
Location (UCSC)	Chr 17: 8.14 – 8.16 Mb	Chr 11: 69.1 – 69.11 Mb
PubMed search	[1]	[2]