Template:PBB/5315

Pyruvate kinase, muscle
PDB rendering based on 1a49.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1T5A, 1ZJH, 3BJF, 3BJT, 3G2G, 3GQY, 3GR4, 3H6O, 3ME3, 3SRD, 3SRF, 3SRH, 3U2Z, 4B2D, 4FXF, 4FXJ, 4G1N, 4JPG, 4QG6, 4QG8, 4QG9, 4QGC, 4RPP
Identifiers
Symbols	PKM ; CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1
External IDs	OMIM: 179050 MGI: 97591 HomoloGene: 37650 ChEMBL: 1075189 GeneCards: PKM Gene
EC number	2.7.1.40
Gene ontology Molecular function • magnesium ion binding • pyruvate kinase activity • protein binding • ATP binding • MHC class II protein complex binding • potassium ion binding • ADP binding • poly(A) RNA binding Cellular component • nucleus • cytoplasm • mitochondrion • cytosol • plasma membrane • cilium • extracellular matrix • vesicle • myelin sheath • extracellular exosome • extracellular vesicle Biological process • response to hypoxia • liver development • carbohydrate metabolic process • glucose metabolic process • ATP biosynthetic process • response to nutrient • response to gravity • programmed cell death • response to muscle inactivity • organ regeneration • response to insulin • pyruvate biosynthetic process • skeletal muscle tissue regeneration • small molecule metabolic process • canonical glycolysis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5315	18746
Ensembl	ENSG00000067225	ENSMUSG00000032294
UniProt	P14618	P52480
RefSeq (mRNA)	NM_001206796	NM_001253883
RefSeq (protein)	NP_001193725	NP_001240812
Location (UCSC)	Chr 15: 72.2 – 72.23 Mb	Chr 9: 59.66 – 59.68 Mb
PubMed search	[1]	[2]