Volociximab

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Volociximab
Monoclonal antibody
Type Whole antibody
Source Chimeric (mouse/human)
Target α5β1 integrin
Identifiers
CAS Number 558480-40-3 N
ATC code none
UNII 496K5Z02NW YesY
KEGG D06319 YesY
Chemical data
Formula C6434H9942N1706O2040S52
Molecular mass 145.5 kDa
 NYesY (what is this?)  (verify)

Volociximab (also known as M200) is a chimeric monoclonal antibody jointly developed by PDL BioPharma and Biogen Idec for treatment of a variety of advanced solid tumors. It binds to and inhibits the functional activity of α5β1 integrin.[1]

It is thought to reduce metastases. Early results show potential in renal cell cancers. [ref needed]

References

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External links


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