Cathepsin L2
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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Cathepsin L2, also known as cathepsin V and encoded by the CTSL2 gene, is a human gene.[1]
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes.
Clinical significance
Cathepsin L2 may play a role in the pathogenesis of keratoconus.[2]
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Kenney, M. C.; Chwa, M.; Atilano, S. R.; Tran, A.; Carballo, M.; Saghizadeh, M.; Vasiliou, V.; Adachi, W.; Brown, D. J. (2005) Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder. Invest. Ophthal. Vis. Sci. 46: 823-832. PMID 15728537
External links
Further reading
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