File:Picolinic acid biosynthesis.png

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Summary

<a href="https://en.wikipedia.org/wiki/Skeletal_structure" class="extiw" title="en:Skeletal structure">Skeletal structures</a> of the <a href="https://en.wikipedia.org/wiki/biosynthesis" class="extiw" title="en:biosynthesis">biosynthesis</a> of L-<a href="https://en.wikipedia.org/wiki/pipecolic_acid" class="extiw" title="en:pipecolic acid">pipecolic acid</a> from L-<a href="https://en.wikipedia.org/wiki/lysine" class="extiw" title="en:lysine">lysine</a> using a <a href="https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide" class="extiw" title="en:Nicotinamide adenine dinucleotide">NAD+/NADH</a> cofactor. The whole process is mediated by the RapL gene in the <a href="https://en.wikipedia.org/wiki/biosynthesis" class="extiw" title="en:biosynthesis">biosynthesis</a> of <a href="https://en.wikipedia.org/wiki/rapamycin" class="extiw" title="en:rapamycin">rapamycin</a>.See Gatto, G. J., Jr.; Boyne, M. T., II; Kelleher,N. L.; Walsh, C. T. (2006). "Biosynthesis of Pipecolic Acid by RapL, a Lysine Cyclodeaminase Encoded in the Rapamycin Gene Cluster". J. Am. Chem. Soc. 128 (11): 3838–3847. <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1021/ja0587603">10.1021/ja0587603</a>. <a href="https://en.wikipedia.org/wiki/PMID" class="extiw" title="w:PMID">PMID</a> <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/pubmed/16536560">16536560</a>.

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File history

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Date/TimeThumbnailDimensionsUserComment
current12:16, 12 January 2017Thumbnail for version as of 12:16, 12 January 20173,155 × 1,527 (71 KB)127.0.0.1 (talk)<a href="https://en.wikipedia.org/wiki/Skeletal_structure" class="extiw" title="en:Skeletal structure">Skeletal structures</a> of the <a href="https://en.wikipedia.org/wiki/biosynthesis" class="extiw" title="en:biosynthesis">biosynthesis</a> of <small>L</small>-<a href="https://en.wikipedia.org/wiki/pipecolic_acid" class="extiw" title="en:pipecolic acid">pipecolic acid</a> from <small>L</small>-<a href="https://en.wikipedia.org/wiki/lysine" class="extiw" title="en:lysine">lysine</a> using a <a href="https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide" class="extiw" title="en:Nicotinamide adenine dinucleotide">NAD+/NADH</a> cofactor. The whole process is mediated by the RapL gene in the <a href="https://en.wikipedia.org/wiki/biosynthesis" class="extiw" title="en:biosynthesis">biosynthesis</a> of <a href="https://en.wikipedia.org/wiki/rapamycin" class="extiw" title="en:rapamycin">rapamycin</a>.See <cite style="font-style:normal">Gatto, G. J., Jr.; Boyne, M. T., II; Kelleher,N. L.; Walsh, C. T. (2006). "Biosynthesis of Pipecolic Acid by RapL, a Lysine Cyclodeaminase Encoded in the Rapamycin Gene Cluster". <i>J. Am. Chem. Soc.</i> <b>128</b> (11): 3838–3847. <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1021/ja0587603">10.1021/ja0587603</a>. <a href="https://en.wikipedia.org/wiki/PMID" class="extiw" title="w:PMID">PMID</a> <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/pubmed/16536560">16536560</a>.</cite>
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