23S rRNA (guanine748-N1)-methyltransferase

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23S rRNA (guanine748-N1)-methyltransferase
Identifiers
EC number 2.1.1.188
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

23S rRNA (guanine748-N1)-methyltransferase (EC 2.1.1.188, Rlma(II), Rlma2, 23S rRNA m1G748 methyltransferase, RlmaII, Rlma II, tylosin-resistance methyltransferase RlmA(II), TlrB, rRNA large subunit methyltransferase II) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine748-N1)-methyltransferase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine748 in 23S rRNA \rightleftharpoons S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA

The enzyme specifically methylates guanine748 at N1 in 23S rRNA.

References

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External links