Anazocine

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Anazocine
File:Anazocine structure.svg
Systematic (IUPAC) name
9-methoxy-3-methyl-9-phenyl-3-azabicyclo[3.3.1]nonane
Identifiers
CAS Number 15378-99-1
21650-02-2 (citrate)
ATC code None
PubChem CID: 27213
ChemSpider 25327
ChEMBL CHEMBL2105792
Chemical data
Formula C16H23NO
Molecular mass 245.360 g/mol
  • O(C2(c1ccccc1)C3CCCC2CN(C3)C)C
  • InChI=1S/C16H23NO/c1-17-11-14-9-6-10-15(12-17)16(14,18-2)13-7-4-3-5-8-13/h3-5,7-8,14-15H,6,9-12H2,1-2H3
  • Key:YFFNPIAPUDUYAU-UHFFFAOYSA-N

Anazocine (INN; CS-307), also known as azabicyclane, is an opioid analgesic of the morphan/benzomorphan family developed in the middle 1960s in the United States which was never marketed.[1][2] It is listed by some sources as a teratogen.[3]

The structure and properties of several related a- and ß-azabicyclane opioids was explored.[4] Anazocine's chemical and structural relatives include opioid partial agonists, mixed agonist-antagonists, pure agonists, antagonists, and atypical non-opioid analgesics. It was tested in pigeons and in other experiments which contrasted and compared its analgesic effects to those of the phenazepine opioid ethoheptazine and the phenalkoxam open chain opioid propoxyphene,[5] and pethidine as well.[6]

See also

References

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  3. https://www.purdue.edu/ehps/rem/ih/terat.htm
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