BCL2L10
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Bcl-2-like protein 10 is a protein that in humans is encoded by the BCL2L10 gene.[1][2][3]
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASP9 related apoptotic pathway.[3]
References
Further reading
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External links
- BCL2L10 human gene location in the UCSC Genome Browser.
- BCL2L10 human gene details in the UCSC Genome Browser.
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