DCP1B

Decapping mRNA 1B
Decapping mRNA 1B
Identifiers
Symbols	DCP1B ; DCP1; hDcp1b
External IDs	OMIM: 609843 MGI: 2442404 HomoloGene: 51881 GeneCards: DCP1B Gene
Gene ontology
Molecular function	• mRNA binding; • protein binding; • hydrolase activity; • enzyme regulator activity;
Cellular component	• cytoplasmic mRNA processing body; • nucleus; • cytoplasm; • cytosol; • membrane; • intracellular membrane-bounded organelle;
Biological process	• nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; • deadenylation-dependent decapping of nuclear-transcribed mRNA; • gene expression; • deadenylation-independent decapping of nuclear-transcribed mRNA; • exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; • regulation of catalytic activity;
	Sources: Amigo / QuickGO
RNA expression pattern
	File:PBB GE DCP1B gnf1h06450 at tn.png
	More reference expression data
Orthologs
Species	Human
Entrez	196513
Ensembl	ENSG00000151065
UniProt	Q8IZD4
RefSeq (mRNA)	NM_152640
RefSeq (protein)	NP_689853
Location (UCSC)	Chr 12:; 1.95 – 2 Mb
PubMed search	[1]
	v; t; e;

mRNA-decapping enzyme 1B is a protein that in humans is encoded by the DCP1B gene.^[1]^[2]^[3]

DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002).[supplied by OMIM]^[3]

References

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