MYL9

Myosin, light chain 9, regulatory
Identifiers
Symbols	MYL9 ; LC20; MLC-2C; MLC2; MRLC1; MYRL2
External IDs	OMIM: 609905 MGI: 1914518 HomoloGene: 21230 GeneCards: MYL9 Gene
Gene ontology Molecular function • calcium ion binding • structural constituent of muscle • myosin heavy chain binding Cellular component • stress fiber • cytosol • muscle myosin complex • Z disc Biological process • muscle contraction • regulation of muscle contraction • small GTPase mediated signal transduction • axon guidance • ephrin receptor signaling pathway • platelet aggregation Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10398	98932
Ensembl	ENSG00000101335	ENSMUSG00000067818
UniProt	P24844	Q9CQ19
RefSeq (mRNA)	NM_006097	NM_172118
RefSeq (protein)	NP_006088	NP_742116
Location (UCSC)	Chr 20: 36.54 – 36.55 Mb	Chr 2: 156.78 – 156.78 Mb
PubMed search	[1]	[2]

Myosin regulatory light polypeptide 9 is a protein that in humans is encoded by the MYL9 gene.

Function

Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.