PABPC1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Polyadenylate-binding protein 1 is a protein that in humans is encoded by the PABPC1 gene.[1]
Function
The poly(A)-binding protein (PAB or PABP), which is found complexed to the 3' poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM][2]
Interactions
PABPC1 has been shown to interact with:
References
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Further reading
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