Paul M. Sharp

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Paul Sharp
Born Paul Martin Sharp
(1957-09-12) 12 September 1957 (age 67)[1]
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Alma mater University of Edinburgh (PhD)
Thesis Quantitative genetics of Drosophila melanogaster - variation in male mating ability (1982)
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Website
www.research.ed.ac.uk/portal/en/persons/paul-sharp(ed91461c-d4f2-497d-8621-2ec9be212726).html

Paul Martin Sharp (born 1957) FRS[14] FRSE[13] MRIA is Professor of Genetics at the University of Edinburgh, where he holds the Alan Robertson chair of genetics in the Institute of Evolutionary Biology.[15][16][17]

Education

Sharp was educated at the University of Edinburgh where he was awarded a Bachelor of Science degree in 1979[12] followed by a PhD in 1982 for research using quantitative genetics on the fruit fly Drosophila melanogaster.[15][18]

Career and research

Sharp has held academic posts at Trinity College, Dublin from 1982 to 1993,[4] the University of Nottingham from 1993 to 2007[4] and was appointed Professor at the University of Edinburgh in 2007.[4]

Sharp's research investigates the evolutionary origin of bacteria and viruses.[14][19][20] He has carried out important work into the origin of HIV and its transmission from chimpanzees to humans. He also discovered that the human malaria parasite, Plasmodium, originated in gorillas.[14] He was one of the first researchers to use DNA sequence databases to gain insight into evolutionary processes. His work amplifying DNA from chimpanzee faecal samples showed that HIV type 1 was transmitted to humans from a specific chimp population in West Africa in the early 20th century. Paul went on to examine his collection of ape faecal samples for plasmodium parasites, finding a likely candidate for the form that causes malaria in humans.[14][21]

In the eighties, Sharp collaborated with Desmond G. Higgins during the creation of CLUSTAL,[9][10] a suite of multiple sequence alignment programs that have become widely used and highly influential.[22] His research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC).[23]

Awards and honours

Sharp was elected member of the European Molecular Biology Organization (EMBO) in 1992,[11] and was President of the Society for Molecular Biology and Evolution[when?]. He was elected member of the Royal Irish Academy in 1993,[12] a Fellow of the Royal Society of Edinburgh (FRSE) in 2010[13] and a Fellow of the Royal Society (FRS) in 2013.[14]

References

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  3. Paul M. Sharp's publications indexed by Google Scholar, a service provided by Google
  4. 4.0 4.1 4.2 4.3 Paul Sharp's Entry at ORCID
  5. Lua error in package.lua at line 80: module 'strict' not found. open access publication - free to read
  6. Lua error in package.lua at line 80: module 'strict' not found. open access publication - free to read
  7. Paul M. Sharp at the Mathematics Genealogy Project
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    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived September 25, 2015)

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  18. Lua error in package.lua at line 80: module 'strict' not found. open access publication - free to read
  19. Paul M. Sharp's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
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