SNAG1

Sorting nexin 18
Identifiers
Symbols	SNX18 ; SH3PX2; SH3PXD3B; SNAG1
External IDs	MGI: 2137642 HomoloGene: 14164 GeneCards: SNX18 Gene
Gene ontology Molecular function • protein binding • phosphatidylinositol-4,5-bisphosphate binding Cellular component • endosome • endosome membrane • cytoplasmic membrane-bounded vesicle • clathrin-coated vesicle • growth cone • cytoplasmic vesicle membrane • extrinsic component of cytoplasmic side of plasma membrane • neuronal cell body • extracellular exosome Biological process • mitotic cytokinesis • intracellular protein transport • endocytosis • mitotic nuclear division • vesicle organization • endosomal transport • cleavage furrow formation • positive regulation of GTPase activity Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	112574	170625
Ensembl	ENSG00000178996	ENSMUSG00000042364
UniProt	Q96RF0	Q91ZR2
RefSeq (mRNA)	NM_001102575	NM_130796
RefSeq (protein)	NP_001096045	NP_570614
Location (UCSC)	Chr 5: 54.52 – 54.55 Mb	Chr 13: 113.59 – 113.62 Mb
PubMed search	[1]	[2]

Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.