ACTR3B

ARP3 actin-related protein 3 homolog B (yeast)
250px PDB rendering based on 1k8k.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1k8k, 1tyq, 1u2v, 2p9i, 2p9k, 2p9l, 2p9n, 2p9p, 2p9s, 2p9u
Identifiers
Symbols	ACTR3B ; ARP11; ARP3BETA
External IDs	MGI: 2661120 HomoloGene: 4180 GeneCards: ACTR3B Gene
Gene ontology Molecular function • molecular_function • actin binding • ATP binding Cellular component • cytoplasm • Arp2/3 protein complex • cell projection • extracellular exosome Biological process • biological_process • Arp2/3 complex-mediated actin nucleation Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE ACTR3B 218868 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	57180	242894
Ensembl	ENSG00000133627	ENSMUSG00000056367
UniProt	Q9P1U1	Q641P0
RefSeq (mRNA)	NM_001040135	NM_001004365
RefSeq (protein)	NP_001035225	NP_001004365
Location (UCSC)	Chr 7: 152.76 – 152.86 Mb	Chr 5: 25.76 – 25.85 Mb
PubMed search	[1]	[2]

Actin-related protein 3B also known as ARP3-beta is a protein that in humans is encoded by the ACTR3B gene. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.

Function

This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.