ACV synthetase
From Infogalactic: the planetary knowledge core
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 6.3.2.26 | ||||||||
CAS number | Template:CAS | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
|
ACV synthetase (ACVS, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase, N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, EC 6.3.2.26) is an enzyme that catalyzes the chemical reaction
- 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O 3 AMP + 3 PPi + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine
The five substrates of this enzyme are ATP, L-2-aminohexanedioate, L-cysteine, L-valine, and H2O, whereas its three products are AMP, diphosphate, and N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine.
ACVS is an example of a nonribosomal peptide synthetase (NRPS). It participates in penicillin and cephalosporin biosyntheses.
References
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
<templatestyles src="Asbox/styles.css"></templatestyles>