Cystic nephroma
From Infogalactic: the planetary knowledge core
| Cystic nephroma | |
|---|---|
| File:Cystic nephroma low mag.jpg
Micrograph of a cystic nephroma (left of image). Normal kidney is seen on the right. H&E stain.
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| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| ICD-10 | D30.0 |
| ICD-9-CM | 223.0 |
| Patient UK | Cystic nephroma |
A cystic nephroma, also known as multilocular cystic nephroma, mixed epithelial stromal tumour (MEST) and renal epithelial stromal tumour (REST),[1] is a type of rare benign kidney tumour.
Contents
Symptoms
Cystic nephromas are often asymptomatic. They are typically discovered on medical imaging incidentally (i.e. an incidentaloma).
Diagnosis
Cystic nephromas are diagnosed by biopsy or excision. It is important to correctly diagnose them as, radiologically, they may mimic the appearance of a renal cell carcinoma that is cystic.[2]
Pathologic diagnosis
File:Cystic nephroma high mag.jpg
High magnification micrograph of a cystic nephroma showing the characteristic simple epithelium with hobnail morphology, and the ovarian-like stroma. H&E stain.
The characteristics of cystic nephromas are:
- Cysts lined by a simple epithelium with a hobnail morphology, i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts,
- Ovarian-like stroma that has a:
- Spindle cell morphology, and has a
- Basophilic cytoplasm.
Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for:
Differential diagnosis
- cystic partially differentiated nephroblastoma
- cystic standard nephroblastoma (cystic Wilm's tumor)
- cystic mesoblastic nephroma
- cystic renal cell carcinoma
- other renal cysts
Additional images
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Cystic nephroma intermed mag.jpg
Micrograph of a cystic nephroma. H&E stain.
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Small JE et al. Cystic Nephroma. BrighamRAD Teaching Case Database. URL: http://brighamrad.harvard.edu/Cases/bwh/hcache/385/full.html. Accessed: July 25, 2009.
