GAL3ST3
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Galactose-3-O-sulfotransferase 3 | |||
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Identifiers | |||
Symbols | GAL3ST3 ; GAL3ST-3; GAL3ST2 | ||
External IDs | OMIM: 608234 MGI: 3617843 HomoloGene: 57198 GeneCards: GAL3ST3 Gene | ||
Orthologs | |||
Species | Human | Mouse | |
Entrez | 89792 | 545276 | |
Ensembl | ENSG00000175229 | ENSMUSG00000047658 | |
UniProt | Q96A11 | P61315 | |
RefSeq (mRNA) | NM_033036 | NM_001024717 | |
RefSeq (protein) | NP_149025 | NP_001019888 | |
Location (UCSC) | Chr 11: 66.04 – 66.05 Mb |
Chr 19: 5.3 – 5.31 Mb |
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PubMed search | [1] | [2] | |
Galactose-3-O-sulfotransferase 3 is an enzyme that in humans is encoded by the GAL3ST3 gene.[1][2][3]
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the 3' position of galactose in N-acetyllactosamine in both type 2 (Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branched O-glycans, but not on type 1 or core-1-branched structures. This gene, which has also been referred to as GAL3ST2, is different from the GAL3ST2 gene located on chromosome 2 that encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 3.[3]
References
Further reading
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